1 [        .         .         .         .         :         .         .         .         .         1         .         .         .         .         :         .         .         .         .         2         .         .         .         .         :         .         .         .         .         3         .         .         .         .         :         .         .         .         .         4         .         .         .         .         :         .         .         .         .         5         .         .         .         .         :         .         .        ] 579
 1 RoseRS_1447   100.0%     --------------MGLGRSPGTVIGLLTYL-----AHRYN-RWNADDRRFFARSGEVRQRRAGERVGD-------------------------------VQALVLFTTLEVLSGE--AK------AFDYVNNPPGEIATGPQQSGRPMKEVLRELLRREWPAISGGRKKGAI-------FCCRVDR---------RDISTTYERVVRVVAALASVGGQGK-EMWANLTGGNNVINLALELAA--------TLSGDIARL-----YYVQAENE-------------AAEKCV-----RYTAENSY-------------WVDLPVMPLAL-GRLRQTIIQVLND---------------------NGPISLEDLY--------SYLQNKYWDLSRGLTSKE--TLRNEY-LAPLWKQGLIAEAEGGYV---VGPQWELIRPY--QELLQKARDVTL---TIEKLAEENKDWLEKEEVSWN----------------------------------------------------------------------------------------------------    
 2 Mhar_1707      16.2%     --------MGVWHISGLGISPGALTVPTSSI----YLLLKAAEEGEAKACEFFETSGEWRQKEGILRGF-------------------------------PEGIVIFTSREVVEKKFSRRSDLKDRWF----KNTGKE----ISVPRVACKFIRDIHRELFDQYDLPKI-----------YYLAVDYQ------------DFKKALPVIYHTVNALGTKGGKELWANMVGGTNQINASILTAG--------SLSGAISRY----YYYFEQDIDLLHPDLEKPKG--RLPKGQ------IDLLLSK-------------WFQLPIFDFGW-GEVSNTINSLMEQYN--------------------NALPLEVL---------KEELEKTGMKSQ--------YLAKLT-GSRLIVIENNLVRPGADL---------NHLRS--LLSGDSNSPNN----LSSW-----KKWAAEKGILWQQEMDQNCT-----------------LKKVFP---------------------------------------------------------------------    
 3 AF1865         14.9%     --------MGVYHISGVGFRPGAVTVPLTAV----YTLQIAQALGIEEAKEFFKYSSE-AEKKGSYEMT-------------------------KGI---PEVLVVFTSRDVIEGR--KKLEYKSNWFS---LSGGSE----EKVEKPIVKYLKKLFRHIEKNFNLEFCLKKF-------YLVKVDHQ------------NFDDCFEKI--GVILRALKDK-EVWGNMIGGTNQINLAMLTAG--------AYTATISKY----YYLFQNDVA--LMEPEWIDKPSNKNIRQ-----ATIEILKK-------------WQELPIFNLEM-GSIMKDISNLFG---------------------GRGFVNIREV---------ERILENYGLGKQ--------FLTKFRGRILEF--EEDKVSKGIMFDKIVNLWN--------LISDVDVRNV-----LREWKD---TGVIREVDINEI-----RCD--------------------------------------------------------------------------------------------    
 4 CL1_1958       17.6%     -----MPVLGVYHVSGLGLSPGALTMPLTAV----YILQAAAQMGHNGARDFFRLSGEAGERSGSREKH-------------------------PGM---PEVVIVFDTPEAIDGK--LRLTYDSRWFRGLSNMRQRE----EPIHRPIVKYLCRL----WDCLEGLGVELKRPKHF---YLVKVNRQ------------DFDEVFDR--ATTLFYGIRRK-EVWVNLIGGSNQINLALMIAG--------SYTMVPSRY-----YYVFQDAP--LLEPGWLEKCPRDEHEV---FKCANEILNR-------------WNDLPPLNLGV-GSI---LRSLLERFY---------------TAKGSAYISKSEV---------LDILEKRG------------YTEKFIPKLIEAGYITPVDGDTFTMGPFIERSWRLFGAA--LEHSRIDS-------IGKW-----------RELMGD------------------------SLVEVPFEC-------------------------------------------------------------------    
 5 NIES39_M01160   8.4%     --------MQRQSTTRIGKLKLRNLVMQSDL----PQWVKETPCHIRQNAIFDAHQAYTASRDACFRSI---------RN--------------------PQQTIKFNNSNFTKGT----------WYSQL-TKKLKF-----KASEPIP------------------------------HQCDYGTQ--------------------------LIYRRGK---WFAV-FPEPVIKSHTYSRK--------IIALDPGVR----TFLTGYDGDKVIEIGNGDMG--RITRLC----THLDNLISRSTKVNAKR-----RRSLKK---AA-NRIREKIRNLIDEVH----KKAAHYLTT-----NYGLIFLPRFES-------SSMVAKSRRKIQSKTVRNM-LTWAHY-RFKLI-LKHQAAKRGCVV-LDVGESH-TSKTC--GVCGHRHAKLG----GAKIHKCPHCGSQTPRDANGARNIMLRAL---------RDSSFTVSNDGIAIVTVRALSINVQDCSA------------------------------------------------------    
 6 Csac_0479       6.8%     --MDKTYILPVPEEYQVLARELSKQSGKIYS----KAVSFLKRMNKKGIKISRKTFDRYMEWWIHQKDF--------------------------VL---HSQSKQAAYQQVWTNY--VA------TLRKI-QKAKKKGKDISRIRLPY-----RNKRYNKVVFKESAVHLKGNVLI---FSNKKGY---------KAIVLKDVMIRTTPKYAELIYHHSKKKYYFHVVVEVEGKKN-EKDKG--------VLAIDLGVI----HPMVCFDGQNVLLYNGGVLN--SKLRYRNKKIAEFQEKLSKCQK-NSQR-----YRKLTRAKRRILTKINHQIRDVLEKYT----SHLMGYCVKN----GIGIIVLGDL---------KGIRNGAKHG-KVANQKV--HQWMFK-KVAKR-IEQKAQETCQEF-------------C--------------------------------------VSIS------------------------------------------------------------------------------------------------    
 7 Calkr_2588      5.9%     -------MITIQSKLIFDSSEDKQTVFDLMR-----RWSDCMRYAYKRLLEGHKRNELKKQLQGIFNLNSRYVDDAIMKANSVLKSCKERGENPRKVIFGGRELFEKLQKRHINGR--AYRKLQCEWQE---KRKGNLY---SRGDKNKKGNLNTRIEIDGS-LTKLRINVGERDYVY--ATIQPGWKVKGGTYTDRNMLLQAISTSGEPYSVEL-KLKNG-AVYAYFTVEEVFPKPKITRANG-------VIGIDTNAYPRQVAWAVTDENGQLLSYGEIPMP--ELESGS-----SSKREYHR-WQ-YAQMIVAIAKEKQKAI--VI-EKLDIQDRGRRGDFSGRKSRRIRHYF-------GYRSL-LEKVRLLAKREGVEVIEVDPAY--TSVIGMLK-YAPQFM-VSKDVAAAYVIARRGLDLKEKVPHNYMELLSRLDANSLEELKEH-----VKKTVKNPNVRKKQLREIDWAIKILQSSGSEPGRLSEPLDGTSEDGRRKDTCN-----LWRVLRAAVVTPLSPDRVLRDMSVLKSLLVSGQVGRPRFGASSCFLGQGLKASQIPPAGAGKS    
 8 LS215_0610      8.2%     ----MERTIKLRVRVDYITYSALKEVEGEYR----EVLEDAI-----NYGLSNKTTSFTRIKAGVYKTE---------RE---------KH---KDL---PSHYIYTACEDASERL--DS------FEK-L-KKRGRSYTEKPSVRKITV-HLDDHL-WKFS-LDKISISTMQGR-----VFISPTFP--------KIFWEYYNTEWRIASEARFKLLKGN-VVEFFIVFKRDEPKP-YEPKG--------FIPVDLNED----SVSVLVDGK------PMLLE--TNTKRI-----TLGYEYRRKAI-TTGR-----STKDREVKRKL-KRLRERDKKV--DIR----RKLAKLIVKEAFE-SMSAIVLEDLPRRTP----EHMIKDVKD--SQLRLRI--YRSAFS-SMKNA-IIEKAKEFRVPV-VLVNPSY-TSSTC--PIHGAKIVYQPDGGDAPRVGVCEKGKEKWHRDVVALYNLRKRAG--------DVSPVPLGSKESHDPPTVKLGRWLRAKSLHSIMNEHKMIEMKV-----------------------------------------    
 9 YG5714_0689     8.6%     --------MKLRVRVDYSTYSALKEVEEEYR----EVLEEAI-----NYGLVNKTTSFTRIKAGVYKTE---------RE---------KH---KNL---PSHYIYTACEDASERL--DS------FEK-L-KKRGRSYTEKPSVRKVTV-HLDDHL-WKFN-LDTISISTKRSR-----VFISPTFP--------KIFWRYYNKGWRIASEARFKLLKGN-VVEFYVIFKKDEPKP-YEPKG--------FIPVDLNEN----SVSVLVDGK------PMLLE--TNTKRI-----TLGYEYRRKAI-TTGK-----PTKDREVRRKL-KRLRERDKKV--DIR----RKLAKLIVIEAFE-SMSAIVLEDLPRRTP----EHMIKDVKD--KQLRLRI--YRSAFS-SMKNV-IIEKAREFGVPV-VLVNPSY-TSTVC--PIHGAKIVYQLDGGDAPRVGVCEKGKEKWHRDVVALYNLAKRAG--------DVSPVPLGSKESHDPPI----RWLRAKSLHSIMNEHKMIEMKV-----------------------------------------    
10 YG5714_0736     9.1%     -------------------------------------------MVERKCPEPGREGSAFESPRGVVREV---------KG---------D-----NL---PSKVAEDCYREALATY--KG------WYN-N-PRRGRF----PRVYRPTV-WLTPRASYNVD-FEAMTVRIVSVG-----ELSILGYP--------RNLKEYM--GWKM-KEARL-VIRDD-KAFLKVVFEKEEQK--VEPKE--------SIAVDINMA----EVVVGKDDK-NYVRIPTRLE--EVHHWK-----SLAERLLKK---YPRR-----WRENKRILYRV-RSFHLKARRIMEDFA----RKVGKWIVDVAKRMGVNVIKLESL---------KNLIKSVEKLSKEFRDKL--YLMQYR-RLQYW-ISWQAKKRGMTV-EFVNPSY-SSVSC--PKCGKRMVEV-----SHRWFKCS-CGYENDRDVIAITNLNGRGS---------LTLSTAPQMRDVNPN-----R--------------------------------------------------------------    
11 SiL_0796        9.7%     MARR-VKAIRATVSMKIAVSDSLLALVINYV----KALRFTLFWLKENVPNPNEKGVLGKVHEELYTRL---------RE---------EY----NL---PSKVVEDCYRDVLSVY--KG------WYN-N-PKKGRF----PRVYKPTV-WLTPKASYSVN-FERMTVRIAGVG-----ELQILGYP--------RNLKEYL--SWKM-KEARL-VVKDG-KAFLKVVFEKEGEK--VEARE--------SIAVDINMS----EIVVGKDDI-HYVRIPTRLH--EVHHWK-----SLTESLQRK---YPGR-----WRESKGILYRI-RSFHQKAKRIMEDFA----RKVGRWVVEIARDFGANVVKLENL---------ENLIKNVDRLPREFRDKL--YLMQYR-RIQYW-IVWQAKKRGILV-EFVNPSY-SSVLC--PRCGRRMEER-----GYRWFKCS-CGYENDRDVVAVVNLNGRGS---------LALSSAHQMRDVVPN-----RW-------------------------------------------------------------    
12 YG5714_0642     9.6%     MARRGNKAIRATVSMKIALSEPLLVLMNNYV----KALRFTLFWLKENVPNPNEDGVISKVHEELYTRL---------RE---------EY----NL---PSKVAEDCYRDALSVY--KG------WYN-N-PKKGRF----PRVYKPTV-WLTPKASYNVD-FEAMTVRIASVG-----ELPILGYP--------RNLKDYM--SWKM-KEARL-VIRND-KAFLKVVFEKKKEK--VEPKE--------SIAIDINMS----EIVVGKDDE-HYVRIPTRLH--EVHHWK-----SLAENLQKK---YPRR-----WRENKRILYRV-RSFNLKARRIMEDFA----RKVGKWVIEIAEDFGANVIKLENL---------RNLIKNVDKLPKEFRDKL--YLMQYR-RLQYW-ISWQARKHGMIV-KFVNPRY-SSVSC--PKCGRKMREV-----SHRWFRCS-CGYENDRDVIAIVNLNRRGS---------LTPSSAHQMRDVAPN-----RWWER----------------------------------------------------------    
13 YN1551_2428     9.6%     MARRGNKAIRATVSMKIAVSDSLLVLVNNYV----KALRFTLFWLKENVPNPNEDGVISKVHEELYTRL---------RE---------EY----NL---PSKVAEDCYRDALSVY--KG------WYN-N-PKKGRF----PRVYKPTV-WLTPKASYNVD-FEAMTVRIASVG-----ELPILGYP--------RNLKDYM--SWKM-KEARL-VIRND-KAFLKVVFEKKKEK--VEPKE--------SIAIDINMS----EIVVGKDDE-HYVRIPTRLH--EVHHWK-----SLAENLQKK---YPRR-----WRENKRILYRV-RSFNLKARRIMEDFA----RKVGKWVIEIAEDFGANVIKLENL---------RNLIKNVDKLPKEFRDKL--YLMQYR-RLQYW-ISWQARKHGMIV-KFVNPRY-SSVSC--PKCGRKMREV-----SHRWFRCS-CGYENDRDVIAIVNLNRRGS---------LTPSSAHQMRDVAPN-----RWWER----------------------------------------------------------    
14 Btus_1371       8.0%     --------MKILKSFRFRLEPTTEQSQCVTR----YRGCARLVWNKALALQKGRLEAGYPLLS--YEELALLLTLWRHSE---------EYGFLTNA---PVHPLQWTLKFLDRAI--RA------AFDK--SNPARFPTFKKKNRDEAGLRFPDPKQIKLD-LSTKDADGRCVLPKV--FLPKIGWV----------KFRKSQTIDGTIRNATV-TWQAG-HWYISFQTEIDVPEP-VHPSES-------AVGIDRGIV----HFAALSDGT-FVDAPGWFRRHETKLAWE-------MRKLSRKKR-FSRN-----WQKQKA---RI-QRLHAHIANARRDFL----HKTSTAISK-----THAMVFVEDLRIQNMSRSAKGTRENPGKNVRAKSGLNKAILDQGWFMFQTF-LDYKLHWFGGWL-GTVPASY-TSQTCPVPECGHVSQANRP---RQSTFRCERCGYEGNADTVGAINILRAGL----------------ARIACSPV--------------------------------------------------------------------    
15 CYB_0598        9.9%     ------MTQVLTVSCKLKVSQSQAAKLDATM----EAFGQALNWVNQNTPEKVANAV--KLQSLCYREI---------RA---------RF----GL---SSNLAQQVCRRLAGAR--KV----------A-RQKNRPVKVFKGGFATYDARIFSFREKDWT-VSLTTVEGRER------FELAIGRY------------QREQLTGSNPKSATLVKRKDG-SYFIQICVEAE-PSPPQRTGR--------VLGVDLGRT----DIAHTSEGD------NWNGQ--QLNKVR-DHYSRLRAVLQR--K-ASKG-----TRSSRRRCRQLLQRLSGKERRFQAWVN----HRISKAIVSRAKT-TNSAIALEDL---------TGIRERVNQQPRGKTECRRANSWAFY-QLRMF-VAYKAAIAGVPV-VLVSPAY-TSQTC--HRCLHIHPDPTQSYRSGKSFKCGHCGWEGDADLNGANVIALLGA----VVNQPRGPGLFCSLVEQNRLRATESPLRTA----------------------------------------------------------    
16 CYA_0887        9.0%     ------MTQVLTVSCKLKASQSQAAKLDATL----EAFGQALNWVNQNTPEKVANAV--KLQSLCYREI---------RA---------RF----GL---SSNLAQQVCRRLAGAR--KV----------A-QQKNRPVKAFKRGFATYDARIFSFREKDWT-VSLTTVEGRER------FELAIGRY------------QRERLAGSNPKSATLVKHKDG-SYSIQICVETE-PSPPQRTGR--------VLGVDLGRT----DIAHTSEGD------NWNGQ--QLNRIR-DHYSKLRAALQRK---ASKG-----TRSSRRRCRQLLQRLSGKERRFQTWVN----HRISKAIVSRAKA-TNSAIALEDL---------TGIRERVNQQPRSKAERRRANSWAFY-QLRQF-LEYKALRAGVAL-ILVPPAY-TSQTC--HRCLHIHPDPAQSYRSGKKFKCGHCGWEGDADLNGANVIALLGA----AVNQPRGSWLACQLQGYRKPALYCEAVRVG----------------------------------------------------------    
17 Marky_1915      5.0%     ---MGAKNEKIKASLAETRARRENQRPRTFV-----LKLQNLSKNKERTLERAFLEAKWLTNWIIADIERLQLPLNKVHEVEAKAGDALEPCKLRVL---GAQVKQRIGRRIQEDL--RG------LHA-L-KQNGHKVG--RLGFKRRV-DAIPFSNQAFT-LRSRGKENRV-------HLQKLGEF--------RALGLHQIPQKAEVANAVLVRKPSGHYLHVTVYVPKDEPKPLPDPGNPNQATDFKAVGVDLGLK----NQAALSNGF----VLRWRVR--ETDRLK-----KLQRKLSRKKK-GSKN-----REHVVH---RI-RREHEKLRWIKQDIR----NRVLALLR------QYDLVAVQ-----------PDRIKGWQ------------ALWGGKVQGAALGGLLEALRTRLPTLVATERNAPTTRTC--SSCGHLNPKVPL---DRRVFTCEACGFRIDRDLNAALNVLTMAW--------PAARALGLDRPEVTPL-----EWEAAGRILGPNPRIRLSHAT------------------------------------------    
18 Osc7112_0505    7.0%     -------MFAVKRALKLNNREATLMAKHAGFRRVVFNMGLSLRTQMYGEGQFTDSKVLNEVKKVLTNYV---------KK-------QPEFAWMNQL---SSRVYQNAFIDLKDAF--RR------YRS---GKAGHP----KFASRRWGQSFTVDSSKGKVLLNAGSTI----------KIPTLGTF------------RLYEALECGYVSQTFTISKEGSRWFVSFCVDAERL-PVQQSES--------SVGIDVGIN----SFATLSTQQ-VFDAPKPLKQ--AKTKLA-----TLQRQASKQVR-GSQN-----QRKTYD---KI-RRLHTRIANIRLDFL----HKLTTYLAQ-----TFKLIKIENLNV-------QGMMAN-----HKLAGAI--SDLGFY-EFKRL-LDYKCKMYGANL-VLVDQWFPSTKTC--SNCGTKKDMPL----SIRTFDCPACGISLDRDLNASLNIL---------------------------------NWEPSA---------------------------------------------------------    
19 SiRe_0885       7.5%     MWRAKEKNDKTQLSFKYKIYPTREVEEKLIKVMQIEAKVYNALLDVVNNARKEGKKITPKDTQNMLRDL-------------------------------KIEGKELVYSKALQMVNNQL------WYNINALHELRKKG--KKVGKLRYKKIMKIINYNQSGFKVEGDKL---------ILSKIGEI----------KVLFHRPLEGEVKGVIIKKSVTG---WYAIFQVEVEKKPLEKAGK--------VVGIDLGVE----KLVTTSDGV-VIENPKVFDK--VERRIK-----ILQQSLSRKKK-GSRN-----YEKVRK---KL-AKLHEHVKNVMSDYI----HKVTSWLVE-----EYDEIYVEDLDV-------KDIVEDSES--KVLRKHI--LHSNFS-KFVSY-LSYKAERAGRRV-VKVDPRN-TSKTC--ARCGYVKKDLTL---ADRIFSCPKCGWAVDRDYNASLNILRAGS------GLPLEPVDRGPLLYIPFSEGVYSKFLGRSRKSPS----------------------------------------------------    
20 SSO1504         9.3%     ---MPTLGFRFRAYTDEQTLRALKAQLKSAC-----KIYNTLRWADIYFYQRDGKGLTRTELRQLALDL---------RK---------QDDEYKQL---YSQVVQQVADRYYEAK--KR------FFEGL----AHF----PKEKKPHKHYSLVYPQYGWKILQVREIRKGSKKKLITLKLSNLGTF--------KVIVHRDFPLDKV-KRVVVKLTRSE-RIYITFVVDHEFPKL-PNTGK--------VVAIDVGVE----KLIVTSDGE-YFPNLRPYEK--ALWKVK-----HLHRELSRKKF-LSHN-----WFKAKV---KL-ARAYEYLKNLRTDLY----MKLGKWFAE-----HYDVVVMEGIHV-------KQLIGKS-L--RSLRRRL--SDVAFS-ELRDL-IKYQLEKYGKKL-ILVNPAY-TSKTC--AKCGYVKEDLSL---SDRVFVCPNCGWIADRDYNASLNILRGSG-------------------SERPL-----VWSSALYQYSGMAEL------------------------------------------------    
   consensus/90%            ..........h....t..............h    ..h..t......t.....t.t......t..hp.............       ..........   .tthh..s..ph.thh  ........h........tc.........t.h..............hp..th.........  .....sh.        .....h.....t...th.h.hhpst..h.h.hhh.t...p.....tt.       .lshshsh.    .hhh..-s...........t..t..ph. .....ht..hp+... ....     ..p......th.tph..p.tph...h.    ..............t.s.l.lptl.....    pthhtp.....p...........th...h..h.h...h...sh.h...h.........t  ..p..............ph.....ht....t-h.h.........    ...............................................